13463-67-7 titanium dioxide suppliers

In the panoramic view of global industrialization, TIO2 factories emerge as a beacon of innovation and progress. These establishments, dedicated to the production of titanium dioxide, play a pivotal role in shaping the modern world's technological landscape. Titanium dioxide, often referred to as TIO2, is not just another chemical compound; it is a cornerstone in various industries, from paints to sunscreens, from cosmetics to solar cells.

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In a 2020 study published in the Journal of Trace Elements in Medicine and Biology, researchers conducted an in vitro experiment to analyze the effects of TiO2 nanoparticles on a human neuroblastoma (SH-SY5Y) cell line. The scientists evaluated “reactive oxygen species (ROS) generation, apoptosis, cellular antioxidant response, endoplasmic reticulum stress and autophagy.” The results showed that exposure to the nanoparticles “induced ROS generation in a dose dependent manner, with values reaching up to 10 fold those of controls. Nrf2 nuclear localization and autophagy also increased in a dose dependent manner. Apoptosis increased by 4- to 10-fold compared to the control group, depending on the dose employed.” 

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